Interventional Radiologist Medical Expert Witness

Education

• 1996
  Bachelor of Medicine and Surgery (MBBCh) (Cum Laude)
  Medicine and Surgery
  University of the Witwatersrand,
  Johannesburg, South Africa
• 2013
  Master of Public
  Health (MPH)
  Clinical Effectiveness,
  Biostatistics, Epidemiology, Health Policy and Management
  Harvard School of Public Health

Postdoctoral Training

• 01/97-12/97 Intern Medicine/Surgery/ObGyn
  Helen Joseph Hospital, Johannesburg, South Africa
• 01/98-01/99 Resident Medicine
  Wellington Hospital, Wellington, New Zealand
• 02/99-01/00 Senior Resident Surgery/Emergency Medicine
  Royal Melbourne Hospital, Melbourne, Australia
• 02/00-02/04 Resident Diagnostic Radiology
  Austin Health, Melbourne, Australia
• 03/04-06/04 Clinical Fellow Interventional Radiology
  Austin Health, Melbourne, Australia
• 07/04-10/06 Clinical Fellow Abdominal Imaging & Intervention
  Massachusetts General Hospital, Boston, MA

Faculty Academic Appointments

• 10/06-01/15 Instructor Radiology
  Harvard Medical School, Boston, MA/Non-voting
• 02/15-present Assistant Professor Radiology
  Harvard Medical School, Boston,MA/Non-voting

Appointments at Hospitals/Affiliated Institutions

• Current
  10/06- Radiologist Radiology/Abdominal,Radiology/Interventional Massachusetts General Hospital
• Past
  12/06-06/16 Radiologist Radiology Cambridge Hospital

Other Professional Positions

• 2013- Chair, Ultrasound RSNA Quantitative Imaging Biomarkers Alliance Ultrasound Clinical Committee 4 days per year
• 2013-2013 Invited board member International Task Force for the Classification of Thyroid Nodule Core Biopsy Histopathology
  1 day per year
• 2014-2014 Invited committee member CEUS LI-RADS working group USA 1 day per year
• 2014-2015 Advisory Panel Pfizer 3 days per year
• 2016- Principal Medical Adviser, Ultrasound General Electric Corporation 5 days per year
• 2016- Scientific Advisory Board Remedy Medical 2 days per year
• 2016- Co-Chair, Imaging Foundation for the National Institutes of Health, NIMBLE (Noninvasive Biomarkers of Metabolic Liver Disease) Consortium 10 days per year 2 days per year
• 2017- Scientific Advisor Crohn’s and Colitis Foundation
• 2018- Co-Chair, Planning Committee IBD Biomarkers Conference, Crohn’s and Colitis Foundation 5 days per year
• 2018 Advisory Panel Bristol Myers Squibb 2 days per year

Major Administrative Leadership Positions

Local
2009-2017 Associate Medical Director, Ultrasound
Massachusetts General Hospital/Radiology
2014- Director, Center for Ultrasound Research & Translation
Massachusetts General Hospital/Radiology
2016- Co-director, Fibrosis Imaging Center, I3
Massachusetts General Hospital/Radiology
2017- Course director, Foundations of Translational Imaging Research Course
Massachusetts General Hospital/Radiology
2017- Service Chief, Body Ultrasound
Massachusetts General Hospital/Radiology

National

2016- Co-chair: Imaging workstream, Non-invasive
Metabolic Biomarkers of Liver Disease (NIMBLE) consortium
Foundation for the National Institutes of Health

Committee Service

2016- Shear Wave Elastography Clinical Committee
Radiological Society of North America
Quantitative Imaging Biomarkers Alliance/Co-chair
2016- Radiology Representative
MGH Executive Committee on Research
2017- PhD Thesis Committee (Chai Mutsalklisana,student)
Massachusetts General Hospital/Radiology/Northeastern University/member
2017- Ultrasound Coordinating Committee
Radiological Society of North America
Quantitative Imaging Biomarkers Alliance/member
2017- Disease Focused Panel: Liver Fibrosis Society of Abdominal Radiology/member
2018- Inflammatory Bowel Disease Biomarkers Conference Committee
Crohns and Colitis Foundation, Co-chair

Professional Societies

2001- Radiological Society of North America Member
2004- American College of Radiology Member
2005-2008 Society of Uroradiology Member
2006- American Roentgen Ray Society Member
2009- American Institute of Ultrasound in Medicine Member
2009- Society of Radiologists in Ultrasound Member
2009-2015 Society of Interventional Radiology Member
2010-2011 New England Roentgen Ray Society Member
2014- Society of Abdominal Radiology Member
2017- American Medical Association Member

Grant Review Activities

2018- Rehabilitation Engineering and Prosthetics/Orthotics Panel
Veterans Affairs/Ad-hoc member
2018 Clinical and Translational Science Institute Grant review committee
USC Southern California Clinical and Translational Science Institute/ad-hoc member review panel
2018- Harvard Catalyst Ideation Challenge: Good Questions Meet Good Data
Harvard Clinical and Translational
Science Center/Ad-hoc member, review panel

Editorial/Reviewer Activities
Ad hoc Reviewer

Journal
Journal of Vascular and Interventional Radiology
American Journal of Roentgenology
Journal of Medical Imaging and Radiation Oncology
Abdominal Imaging
Journal of Ultrasound in Medicine
Ultrasound in Medicine and Biology

Honors and Prizes

1991-1996 Standard Bank Scholarship
University of the Witwatersrand
Academic merit tuition scholarship
1992 EJA Loerincz Scholarship
University of the Witwatersrand
Academic merit tuition scholarship
1993 Efamed Prize for Biochemistry
University of the Witwatersrand
First placed student in Biochemistry
1995 Society of Anesthesiologists Medal
University of the Witwatersrand
First placed student in Anesthesiology
1996 Nestle Prize University of the Witwatersrand
First placed student in Pediatrics
1996 Medical Graduates Association Medal
University of the Witwatersrand
First placed student in Medicine
1998 Australian Medical Council
Australian Medical Council
Highest score in Australia on medical licensure examinations
2002 Young Inventor of the Year Prize
Dow Jones Media (Far Eastern Economic Review)
Invention of a laser-guidance system for interventional radiology procedures in CT
2004 Siemens Australia Research Prize
Siemens Australia
Invention of a laser-guidance system for interventional radiology procedures in ultrasound
2006 ABC Television New Inventors Prize
ABC Television Invention of a laser-guidance system for interventional radiology procedures in ultrasound
2008 Cum Laude Award Society of Computed Body Tomography/MRI
Cum Laude award for poster presentation at annual meeting
2010 Cum Laude Award Radiologic Society of North America
Cum Laude award for poster presentation at annual meeting
2011 Certificate of Merit
Radiologic Society of North America
Certificate of Merit for Education Exhibit
2011 Member in Training Award
Society of Radiologists in Ultrasound
Member in Training award for poster presentation at annual meeting
2012 Certificate of Merit
Radiologic Society of North America
Certificate of Merit for Education Exhibit
2014 Cum Laude Award Radiologic Society of North America
Two awards for poster presentations at annual meeting
2015 Howard S. Stern Research Award
Society of Abdominal Radiology
$15,000 Research Award

Formal Teaching of Residents, Clinical Fellows and Research Fellows (post-docs)

2006-present Thyroid and Parathyroid Ultrasound Massachusetts General Hospital
Fellows and Residents in Endocrinology 40 Residents, 15 Fellows, one hour lecture,(given annually)
2006-present Testicular Ultrasound Massachusetts General Hospital
Fellows and Residents in Radiology 40 Residents, 15 Fellows, one hour lecture,(given annually)
2008-present Ultrasound of Transplantation Medicine Massachusetts General Hospital
Fellows and Residents in Radiology 40 Residents, 15 Fellows, one hour lecture,(given annually)

Clinical Supervisory and Training Responsibilities

2006- Supervise residents and fellows in clinical work
MGH White 2 Ultrasound, Ellison 2 Interventional Radiology
Average 8 hours per week

Laboratory and Other Research Supervisory and Training Responsibilities

Year Role/Location Time allocated
2006- Fellow advisor – research projects
MGH White 2 Ultrasound Average 24 hours per week

Report of Clinical Activities and Innovations Current Licensure and Certification

Practice Activities
2006- Abdominal
Imaging/Diagnostic Ultrasound Division of Ultrasound,
Massachusetts General Hospital Two 4-hour sessions per week
2006-2017 Abdominal Imaging & Interventional Radiology
Department of Radiology,
Massachusetts General Hospital Four 4-hour sessions per week
2006-2016 Interventional Radiology
Department of Radiology,
Cambridge Hospital On-call coverage, average 1.5 days per week

Significant Supporting Activities

Administration and Institutional service. (a) Administrative leadership. I provide administrative leadership as the Service Chief for Body Ultrasound, where I my responsibilities include medical oversight of 50 sonographers, a technical manager, and an operations manager, who perform ~70,000 sonograms per year at 10 practice locations. The MGH Division of Ultrasound has maintained excellent productivity, clinical standards, and morale during my tenure. I have been directly responsible for bringing advanced ultrasound technologies into clinical practice at MGH, including shear wave elastography, which is now widely used for liver disease risk stratification and contrast enhanced ultrasound, which is used for liver lesion characterization. (b) Faculty mentorship. I presently mentor three MGH Radiology Faculty outside my research group. I assist these faculty with career strategy, grant preparation, and creative ideation, with excellent outcomes. The two faculty mentees who have applied to date have both received career development awards.

Investigation. My research group and others pioneered shear wave ultrasound elastography in the United States, generating key early evidence for use of the technique in chronic liver disease. More recently, through NIH-supported work, we have shown that quantitative ultrasound parameters can be used to detect ischemia in candidate transplant graft livers and that convolutional neural networks can be used to automate and improve the performance of shear wave elastography in the liver and breast. My work in data analysis combines with my interests in electromechanical device design to produce medical devices guided by advanced signal processing. My group has collaboratively developed multiple prototype medical devices and in the past four years I have published multiple senior author papers in the clinical and engineering literature in fields as diverse as translational research, device engineering, ultrasound physics, signal processing, and statistical methods.

Contributions in Teaching

Foundations of Translational Imaging Research Training Program. I established a training program for postdoctoral research fellows in 2016. This program comprises a combination of didactic teaching, mentored research, and self-directed reading. More than thirty post-doctoral fellows have gone through this program and have benefited from instruction focused specifically on the needs of junior imaging researchers.’
Radiology resident teaching. I routinely teach Radiology residents at the viewing workstation for approximately 8 hours per week. I also lecture at the Radiology resident review series and provide informal examination tutorials in the field of medical ultrasound.

Lecturing. I lecture on ultrasound physics at the Harvard/MIT HST program and periodically lecture in MIT engineering courses regarding technology translation.
Abdominal Imaging textbooks. I co-edited a comprehensive subspecialty Radiology textbook, Abdominal Imaging, Expert Consult, published by Elsevier in 2010. This book comprises 1,600 pages over two volumes and is a widely-used reference text in the USA and internationally. I was extensively involved in this book and authored 11 chapters. A Spanish Edition was released in 2013, and the second edition was released in September 2016. I am presently under contract with Elsevier to produce another book, the Abdominal Imaging Requisites, targeted for release in 2020. These books have served as a mechanism to amplify and spread my teaching activities beyond the MGH, MIT, and Harvard Medical School.